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Structural basis of a Ni acquisition cycle for [NiFe] hydrogenase by Ni-metallochaperone HypA and its enhancer

The Ni atom at the catalytic center of [NiFe] hydrogenases is incorporated by a Ni-metallochaperone, HypA, and a GTPase/ATPase, HypB. We report the crystal structures of the transient complex formed between HypA and ATPase-type HypB (HypB(AT)) with Ni ions. Transient association between HypA and Hyp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Watanabe, Satoshi, Kawashima, Takumi, Nishitani, Yuichi, Kanai, Tamotsu, Wada, Takehiko, Inaba, Kenji, Atomi, Haruyuki, Imanaka, Tadayuki, Miki, Kunio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485131/
https://ncbi.nlm.nih.gov/pubmed/26056269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503102112
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