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Hyperglycemia increases the expression levels of sclerostin in a reactive oxygen species- and tumor necrosis factor-alpha-dependent manner
PURPOSE: Sclerostin, an inhibitor of Wnt/β-catenin signaling, exerts negative effects on bone formation and contributes to periodontitis-induced alveolar bone loss. Recent studies have demonstrated that serum sclerostin levels are increased in diabetic patients and that sclerostin expression in alve...
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| 發表在: | J Periodontal Implant Sci |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Korean Academy of Periodontology
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4485060/ https://ncbi.nlm.nih.gov/pubmed/26131370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5051/jpis.2015.45.3.101 |
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