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Clinical Severity of PGK1 Deficiency Due To a Novel p.E120K Substitution Is Exacerbated by Co-inheritance of a Subclinical Translocation t(3;14)(q26.33;q12), Disrupting NUBPL Gene

Carriers of cytogenetically similar, apparently balanced familial chromosome translocations not always exhibit the putative translocation-associated disease phenotype. Additional genetic defects, such as genomic imbalance at breakpoint regions or elsewhere in the genome, have been reported as the mo...

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Publicado en:JIMD Rep
Main Authors: David, Dezső, Almeida, Lígia S., Maggi, Maristella, Araújo, Carlos, Imreh, Stefan, Valentini, Giovanna, Fekete, György, Haltrich, Irén
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484905/
https://ncbi.nlm.nih.gov/pubmed/25814383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2015_427
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