Telomere Shortening in Down Syndrome Patients—When Does It Start?

Down syndrome (DS) is one of the most common aneuploidy. In general population, its prevalence is 1:600–1:800 live births. It is caused by a trisomy of chromosome 21. DS is phenotypically manifested by premature aging, upward slant to the eyes, epicanthus, flattened face, and poor muscle tone. In ad...

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Detalhes bibliográficos
Publicado no:DNA Cell Biol
Main Authors: Gruszecka, Aleksandra, Kopczyński, Przemysław, Cudziło, Dorota, Lipińska, Natalia, Romaniuk, Aleksandra, Barczak, Wojciech, Rozwadowska, Natalia, Totoń, Ewa, Rubiś, Błażej
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Molecular Genetics/Genomics/Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484712/
https://ncbi.nlm.nih.gov/pubmed/25786194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2014.2746
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