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Autoimmune response to PARP and BRCA1/BRCA2 in cancer

PURPOSE: To determine the role of autoantibodies to PARP1 and BRCA1/BRCA2 which were involved in the synthetic lethal interaction in cancer. METHODS: Enzyme-Linked Immunosorbent Assay (ELISA) was used to detect autoantibodies to PARP1 and BRCA1/BRCA2 in 618 serum samples including 131 from breast ca...

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Publicat a:Oncotarget
Autors principals: Zhu, Qing, Han, Su-Xia, Zhou, Cong-Ya, Cai, Meng-Jiao, Dai, Li-Ping, Zhang, Jian-Ying
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484477/
https://ncbi.nlm.nih.gov/pubmed/25865228
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