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Reduction in gap junction intercellular communication promotes glioma migration

Glioblastoma Multiforme (GBM), an aggressive form of adult brain tumor, is difficult to treat due to its invasive nature. One of the molecular changes observed in GBM is a decrease in the expression of the gap junction protein Connexin43 (Cx43); however, how a reduction in Cx43 expression contribute...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Aftab, Qurratulain, Sin, Wun-Chey, Naus, Christian C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484468/
https://ncbi.nlm.nih.gov/pubmed/25926558
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