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Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition

Adrenal carcinoma (ACC) is a rare neoplasm with a poor outcome. Aberrant expression of β-catenin has been found in approximatively 30% of ACC. We herein studied its effects on the growth of the human ACC cell line H295R. The cells were infected with short hairpin RNA (shRNA)-mediated silencing β-cat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Salomon, Aude, Keramidas, Michelle, Maisin, Cécile, Thomas, Michaël
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484466/
https://ncbi.nlm.nih.gov/pubmed/25823656
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