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New somatic mutations and WNK1-B4GALNT3 gene fusion in papillary thyroid carcinoma
Papillary thyroid carcinoma (PTC) is the most frequent thyroid malignant neoplasia. Oncogene activation occurs in more than 70% of the cases. Indeed, about 40% of PTCs harbor mutations in BRAF gene, whereas RET rearrangements (RET/PTC oncogenes) are present in about 20% of cases. Finally, RAS mutati...
Enregistré dans:
Publié dans: | Oncotarget |
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Auteurs principaux: | , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Impact Journals LLC
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4484453/ https://ncbi.nlm.nih.gov/pubmed/25803323 |
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