Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells

Pancreatic Ductal Adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by rapid progression, invasiveness and resistance to treatment. We have previously demonstrated that most PDAC patients have circulating antibodies against the glycolytic enzyme alpha-enolase (ENO1), which correl...

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Publicado en:Oncotarget
Autores principales: Principe, Moitza, Ceruti, Patrizia, Shih, Neng-Yao, Chattaragada, Michelle S., Rolla, Simona, Conti, Laura, Bestagno, Marco, Zentilin, Lorena, Yang, Sheng-Hui, Migliorini, Paola, Cappello, Paola, Burrone, Oscar, Novelli, Francesco
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484442/
https://ncbi.nlm.nih.gov/pubmed/25860938
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