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MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1

miR-146a is a NF-κB induced microRNA that serves as a feedback regulator of this critical pathway. In mice, deficiency of miR-146a results in hematolymphoid cancer at advanced ages as a consequence of constitutive NF-κB activity. In this study, we queried whether the deficiency of miR-146a contribut...

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Publicat a:Oncotarget
Autors principals: Contreras, Jorge R., Palanichamy, Jayanth Kumar, Tran, Tiffany M., Fernando, Thilini R., Rodriguez-Malave, Norma I., Goswami, Neha, Arboleda, Valerie A., Casero, David, Rao, Dinesh S.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484436/
https://ncbi.nlm.nih.gov/pubmed/25906746
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