Leucine-rich α-2-glycoprotein promotes TGFβ1-mediated growth suppression in the Lewis lung carcinoma cell lines

Leucine-rich α2-glycoprotein (LRG) is an approximately 50-kDa glycoprotein that has been found to be elevated in the sera of patients with several types of cancer. LRG directly binds to transforming growth factor beta 1 (TGFβ1) and modulates TGFβ1 signaling in endothelial cells; however, the precise...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Takemoto, Norihiko, Serada, Satoshi, Fujimoto, Minoru, Honda, Hiromi, Ohkawara, Tomoharu, Takahashi, Tsuyoshi, Nomura, Shintaro, Inohara, Hidenori, Naka, Tetsuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484435/
https://ncbi.nlm.nih.gov/pubmed/25826092
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