Electrostatic distance geometry in a K+ channel vestibule.
Many voltage-gated K+ channels carry in the external vestibule a receptor for charybdotoxin, a peptide channel blocker. We use point mutagenesis of both charybdotoxin and a Shaker K+ channel to isolate the electrostatic interaction energy between chosen pairs of residues, one on the channel and one...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1994
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7524078/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.20.9509 |
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