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The downregulation of OPN inhibits proliferation and migration and regulate activation of Erk1/2 in ECA-109 cells

Osteopontin (OPN) involves in tumor formation, and strongly correlated with the tumor progression. It was overexpressed in human esophageal squamous cell carcinoma (ESCC). To study the molecular mechanisms of OPN in ESCC, we examined its roles in inhibiting proliferation and invasion of ECA-109 (eso...

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Bibliografski detalji
Izdano u:Int J Clin Exp Med
Glavni autori: Xu, Song-Tao, Zou, Fa-Zhang, Cai, Li-Na, Xu, Wan-Ling
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2015
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483878/
https://ncbi.nlm.nih.gov/pubmed/26131112
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