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The downregulation of OPN inhibits proliferation and migration and regulate activation of Erk1/2 in ECA-109 cells

Osteopontin (OPN) involves in tumor formation, and strongly correlated with the tumor progression. It was overexpressed in human esophageal squamous cell carcinoma (ESCC). To study the molecular mechanisms of OPN in ESCC, we examined its roles in inhibiting proliferation and invasion of ECA-109 (eso...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Xu, Song-Tao, Zou, Fa-Zhang, Cai, Li-Na, Xu, Wan-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483878/
https://ncbi.nlm.nih.gov/pubmed/26131112
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