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High rate of mismatch extension during reverse transcription in a single round of retrovirus replication.

We made spleen necrosis virus-based retroviral vectors with mutations at the 3' end of the primer binding site region to observe the effects of terminal mismatches on retroviral replication. These vectors, when compared to a vector with the wild-type primer binding sequence, allowed us to assay...

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Bibliografske podrobnosti
Main Authors: Pulsinelli, G A, Temin, H M
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC44838/
https://ncbi.nlm.nih.gov/pubmed/7524077
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