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Lack of a significant change in caffeine metabolism in underweight children as determined by the caffeine breath test

OBJECTIVE: Limited data from pharmacokinetic studies in underweight and severely malnourished children have indicated an impaired activity of their hepatic enzymes. We used the caffeine breath test to assess the metabolising activity of cytochrome P450 1A2 (CYP1A2) enzyme in underweight children. ME...

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Detalhes bibliográficos
Publicado no:Arch Dis Child
Main Authors: Oshikoya, K A, Sammons, H, Smith, K, Choonara, I
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483790/
https://ncbi.nlm.nih.gov/pubmed/25897037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/archdischild-2014-308017
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