Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis

Hair follicle morphogenesis requires precisely controlled reciprocal communications, including hedgehog (Hh) signaling. Activation of the Hh signaling pathway relies on the primary cilium. Disrupting ciliogenesis results in hair follicle morphogenesis defects due to attenuated Hh signaling; however,...

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Библиографические подробности
Опубликовано в: :Development
Главные авторы: Yang, Ning, Li, Li, Eguether, Thibaut, Sundberg, John P., Pazour, Gregory J., Chen, Jiang
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2015
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483764/
https://ncbi.nlm.nih.gov/pubmed/26023097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.115261
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