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Construction of Escherichia coli Mutant with Decreased Endotoxic Activity by Modifying Lipid A Structure
Escherichia coli BL21 (DE3) and its derivatives are widely used for the production of recombinant proteins, but these purified proteins are always contaminated with lipopolysaccharide (LPS). LPS is recognized by the toll-like receptor 4 and myeloid differentiation factor 2 complex of mammalian immun...
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| Publicado no: | Mar Drugs |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4483635/ https://ncbi.nlm.nih.gov/pubmed/26023843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13063388 |
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