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Treatment of Platelet Concentrates with the Mirasol Pathogen Inactivation System Modulates Platelet Oxidative Stress and NF-κB Activation

BACKGROUND: Pathogen inactivation (PI) technologies for platelets aim to improve transfusion safety by preventing the replication of contaminating pathogens. However, as a consequence of treatment, aspects of the platelet storage lesion are amplified. Mirasol treatment also affects platelet signal t...

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Publicado en:Transfus Med Hemother
Autores principales: Johnson, Lacey, Marks, Denese
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger Verlag für Medizin und Naturwissenschaften GmbH 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483294/
https://ncbi.nlm.nih.gov/pubmed/26195930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000403245
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