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Pharmacokinetics of rituximab in a pediatric patient with therapy-resistant nephrotic syndrome

BACKGROUND: Rituximab (RTX) has recently been introduced as a second-line therapy for nephrotic syndrome in children. Studies show that RTX given during the nephrotic state may be less effective than treatment during a non-nephrotic state, possibly due to loss of RTX in the urine. CASE-DIAGNOSIS/TRE...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pediatr Nephrol
Hauptverfasser: Counsilman, Clare E., Jol–van der Zijde, Cornelia M., Stevens, Jasper, Cransberg, Karlien, Bredius, Robbert G. M., Sukhai, Ram N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483248/
https://ncbi.nlm.nih.gov/pubmed/26054711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-015-3120-8
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