Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene.

Although commonly expressed human melanoma-associated antigens recognized by CD8+ cytolytic T cells have been described, little is known about CD4+ T-cell recognition of melanoma-associated antigens. Epstein-Barr virus-transformed B cells were used to present antigens derived from whole cell lysates...

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Autors principals: Topalian, S L, Rivoltini, L, Mancini, M, Markus, N R, Robbins, P F, Kawakami, Y, Rosenberg, S A
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC44832/
https://ncbi.nlm.nih.gov/pubmed/7937789
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