Connexin 30 expression inhibits growth of human malignant gliomas but protects them against radiation therapy

BACKGROUND: Glioblastomas remain ominous tumors that almost invariably escape treatment. Connexins are a family of transmembrane, gap junction-forming proteins, some members of which were reported to act as tumor suppressors and to modulate cellular metabolism in response to cytotoxic stress. METHOD...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Artesi, Maria, Kroonen, Jerome, Bredel, Markus, Nguyen-Khac, Minh, Deprez, Manuel, Schoysman, Laurent, Poulet, Christophe, Chakravarti, Arnab, Kim, Hyunsoo, Scholtens, Denise, Seute, Tatjana, Rogister, Bernard, Bours, Vincent, Robe, Pierre A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483098/
https://ncbi.nlm.nih.gov/pubmed/25155356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou215
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