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Thrombin-processed Ecrg4 recruits myeloid cells and induces antitumorigenic inflammation

BACKGROUND: Extensive infiltration of brain tumors by microglia and macrophages is a hallmark of tumor progression, and yet the overall tumor microenvironment is characterized by an immunosuppressive phenotype. Here we identify esophageal cancer-related gene 4 (Ecrg4) as a novel thrombin-processed m...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Lee, Jisook, Dang, Xitong, Borboa, Alexandra, Coimbra, Raul, Baird, Andrew, Eliceiri, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482854/
https://ncbi.nlm.nih.gov/pubmed/25378632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou302
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