ImmunoPET of Tissue Factor Expression in Triple-Negative Breast Cancer with a Radiolabeled Antibody Fab Fragment

PURPOSE: To date, there is no effective therapy for triple-negative breast cancer (TNBC), which has dismal clinical outcome. Upregulation of tissue factor (TF) expression leads to increased patient morbidity and mortality in many solid tumor types, including TNBC. Our goal is to employ the Fab fragm...

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Pubblicato in:Eur J Nucl Med Mol Imaging
Autori principali: Shi, Sixiang, Hong, Hao, Orbay, Hakan, Graves, Stephen A., Yang, Yunan, Ohman, Jakob D., Liu, Bai, Nickles, Robert J., Wong, Hing C., Cai, Weibo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482783/
https://ncbi.nlm.nih.gov/pubmed/25801992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-015-3038-1
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