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The Impact of IL28B Genotype and Liver Fibrosis on the Hepatic Expression of IP10, IFI27, ISG15, and MX1 and Their Association with Treatment Outcomes in Patients with Chronic Hepatitis C

The strong impact of interleukin 28B (IL28B) polymorphisms on sustained virological response (SVR) after peginterferon and ribavirin treatment in patients with chronic hepatitis C (CHC) is well-known. We investigated IL28B variability and hepatic expression of IP10, IFI27, ISG15, and MX1 in CHC pati...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Domagalski, Krzysztof, Pawłowska, Małgorzata, Kozielewicz, Dorota, Dybowska, Dorota, Tretyn, Andrzej, Halota, Waldemar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482747/
https://ncbi.nlm.nih.gov/pubmed/26115415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130899
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