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Deficiency of Actinin-Associated LIM Protein Alters Regional Right Ventricular Function and Hypertrophic Remodeling

Targeted deletion of actinin-associated LIM protein (ALP) in mice leads to right ventricular (RV) dysplasia and a mild RV cardiomyopathy. Although the phenotype has been thoroughly characterized, the mechanisms leading from the cytoskeletal defect to the disease are unclear. We hypothesized that ALP...

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Dades bibliogràfiques
Publicat a:Ann Biomed Eng
Autors principals: Lorenzen-Schmidt, Ilka, McCulloch, Andrew D., Omens, Jeffrey H.
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482468/
https://ncbi.nlm.nih.gov/pubmed/16060528
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