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Sequence variations at I260 and A1731 contribute to persistent currents in Drosophila sodium channels

Tetrodotoxin-sensitive persistent sodium currents, I(NaP), that activate at subthreshold voltages, have been detected in numerous vertebrate and invertebrate neurons. These currents are believed to be critical for regulating neuronal excitability. However, the molecular mechanism underlying I(NaP) i...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Gao, Rong, Du, Yuzhe, Wang, Lingxin, Nomura, Yoshiko, Satar, Gul, Gordon, Dalia, Gurevitz, Michael, Goldin, Alan L., Dong, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482340/
https://ncbi.nlm.nih.gov/pubmed/24662849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.03.028
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