Acute and subchronic exposure to air particulate matter induces expression of angiotensin and bradykinin-related genes in the lungs and heart: Angiotensin-II type-I receptor as a molecular target of particulate matter exposure

BACKGROUND: Particulate matter (PM) adverse effects on health include lung and heart damage. The renin-angiotensin-aldosterone (RAAS) and kallikrein-kinin (KKS) endocrine systems are involved in the pathophysiology of cardiovascular diseases and have been found to impact lung diseases. The aim of th...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Aztatzi-Aguilar, Octavio Gamaliel, Uribe-Ramírez, Marisela, Arias-Montaño, José Antonio, Barbier, Olivier, De Vizcaya-Ruiz, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482198/
https://ncbi.nlm.nih.gov/pubmed/26113123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-015-0094-4
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