A PHASE 1 STUDY OF GEMCITABINE COMBINED WITH DASATINIB IN PATIENTS WITH ADVANCED SOLID TUMORS

PURPOSE: Dasatinib has been shown preclinically to overcome resistance to gemcitabine. We evaluated the safety and biological activity of the combination of dasatinib and gemcitabine in patients with advanced solid tumors. EXPERIMENTAL DESIGN: In a phase 1 study (3+3 design), patients received daily...

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Bibliografiske detaljer
Udgivet i:Invest New Drugs
Main Authors: Hong, David S., Choe, Jennifer Hsing, Naing, Aung, Wheler, Jennifer J., Falchook, Gerald S., Piha-Paul, Sarina, Moulder, Stacy L., George, Goldy C., Choe, Jonathan M., Strauss, Lewis C., Gallick, Gary E., Kurzrock, Razelle
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482128/
https://ncbi.nlm.nih.gov/pubmed/23179336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-012-9898-3
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