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Breaking and entering into the CNS: clues from solid tumor and nonmalignant models with relevance to hematopoietic malignancies
Various malignancies invade the CNS sanctuary site, accounting for the vast majority of CNS neoplastic foci and contributing to significant morbidity as well as mortality. The blood–brain barrier (BBB) exhibits considerable impermeability to chemotherapeutic agents, severely limiting therapeutic opt...
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| Publicado no: | Clin Exp Metastasis |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4482126/ https://ncbi.nlm.nih.gov/pubmed/24306183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-013-9623-4 |
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