NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway

Trypanosomes mostly regulate gene expression through post-transcriptional mechanisms, particularly mRNA stability. However, much mRNA degradation is cytoplasmic such that mRNA nuclear export must represent an important level of regulation. Ribosomal RNAs must also be exported from the nucleus and th...

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Опубликовано в: :Nucleic Acids Res
Главные авторы: Bühlmann, Melanie, Walrad, Pegine, Rico, Eva, Ivens, Alasdair, Capewell, Paul, Naguleswaran, Arunasalam, Roditi, Isabel, Matthews, Keith R.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Gene regulation, Chromatin and Epigenetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482084/
https://ncbi.nlm.nih.gov/pubmed/25873624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv330
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