Withdrawal From Chronic Nicotine Reduces Thyroid Hormone Levels and Levothyroxine Treatment Ameliorates Nicotine Withdrawal-Induced Deficits in Hippocampus-Dependent Learning in C57BL/6J Mice

INTRODUCTION: Cigarette smoking alters a variety of endocrine systems including thyroid hormones. Altered thyroid hormone signaling may lead to a subclinical or overt hypothyroid condition that could contribute to nicotine withdrawal-related symptoms, such as cognitive deficits. Thus, normalizing th...

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Опубликовано в: :Nicotine Tob Res
Главные авторы: Leach, Prescott T., Holliday, Erica, Kutlu, Munir G., Gould, Thomas J.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
Предметы:
Original Investigation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481724/
https://ncbi.nlm.nih.gov/pubmed/25358661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ntr/ntu229
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