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Effect of Variation in hemorheology between human and animal blood on the binding efficacy of vascular-targeted carriers

Animal models are extensively used to evaluate the in vivo functionality of novel drug delivery systems (DDS). However, many variations likely exist in vivo between the animals and human physiological environment that significantly alter results obtained with animal models relative to human system....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Namdee, K., Carrasco-Teja, M., Fish, M. B., Charoenphol, P., Eniola-Adefeso, O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481524/
https://ncbi.nlm.nih.gov/pubmed/26113000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11631
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