Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cyclooxygenase-2 expression in human colon cancer LoVo cells

AIM: To examine whether lysophosphatidic acid (LPA) induces phosphorylation of c-Met and epidermal growth factor receptor (EGFR), both of which have been proposed as prognostic markers of colorectal cancer, and whether LPA induces cyclooxygenase-2 (COX-2) expression in human colon cancer cells. METH...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Shida, Dai, Kitayama, Joji, Yamaguchi, Hironori, Yamashita, Hiroharu, Mori, Ken, Watanabe, Toshiaki, Nagawa, Hirokazu
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2005
Assuntos:
Colorectal Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481480/
https://ncbi.nlm.nih.gov/pubmed/16237757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i36.5638
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