An Insulator Element Located at the Cyclin B1 Interacting Protein 1 Gene Locus Is Highly Conserved among Mammalian Species

Insulators are cis-elements that control the direction of enhancer and silencer activities (enhancer-blocking) and protect genes from silencing by heterochromatinization (barrier activity). Understanding insulators is critical to elucidate gene regulatory mechanisms at chromosomal domain levels. Her...

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Pubblicato in:PLoS One
Autori principali: Yoshida, Wataru, Tomikawa, Junko, Inaki, Makoto, Kimura, Hiroshi, Onodera, Masafumi, Hata, Kenichiro, Nakabayashi, Kazuhiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481373/
https://ncbi.nlm.nih.gov/pubmed/26110280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131204
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