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Young, proliferative thymic epithelial cells engraft and function in aging thymuses

The thymus reaches its maximum size early in life and then begins to shrink, producing fewer T cells with increasing age. This thymic decline is thought to contribute to age-related T cell lymphopenias and hinder T cell recovery following bone marrow transplantation. While several cellular and molec...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Kim, Mi-Jeong, Miller, Christine M., Shadrach, Jennifer L., Wagers, Amy J., Serwold, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481326/
https://ncbi.nlm.nih.gov/pubmed/25870244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403158
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