Hemagglutinin Sequence Conservation Guided Stem Immunogen Design from Influenza A H3 Subtype

Seasonal epidemics caused by influenza A (H1 and H3 subtypes) and B viruses are a major global health threat. The traditional, trivalent influenza vaccines have limited efficacy because of rapid antigenic evolution of the circulating viruses. This antigenic variability mediates viral escape from the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mallajosyula, V. Vamsee Aditya, Citron, Michael, Ferrara, Francesca, Temperton, Nigel J., Liang, Xiaoping, Flynn, Jessica A., Varadarajan, Raghavan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481277/
https://ncbi.nlm.nih.gov/pubmed/26167164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00329
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