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Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells

Notch signaling is a key regulator of vascular smooth muscle cell (VSMC) phenotypes, including differentiation, proliferation, and cell survival. However, the exact contribution of the individual Notch receptors has not been thoroughly delineated. In this study, we identify unique roles for NOTCH2 a...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Baeten, Jeremy T., Lilly, Brenda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481222/
https://ncbi.nlm.nih.gov/pubmed/25957400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.655548
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