Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets

Cells, the basic units of biological structure and function, vary broadly in type and state. Single-cell genomics can characterize cell identity and function, but limitations of ease and scale have prevented its broad application. Here we describe Drop-Seq, a strategy for quickly profiling thousands...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Macosko, Evan Z., Basu, Anindita, Satija, Rahul, Nemesh, James, Shekhar, Karthik, Goldman, Melissa, Tirosh, Itay, Bialas, Allison R., Kamitaki, Nolan, Martersteck, Emily M., Trombetta, John J., Weitz, David A., Sanes, Joshua R., Shalek, Alex K., Regev, Aviv, McCarroll, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481139/
https://ncbi.nlm.nih.gov/pubmed/26000488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.002
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