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Selecting causal genes from genome-wide association studies via functionally-coherent subnetworks
While genome-wide association (GWA) studies have linked thousands of loci to human diseases, the causal genes and variants at these loci generally remain unknown. Although investigators typically focus on genes closest to the associated polymorphisms, the causal gene is often more distal. Relying on...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480866/ https://ncbi.nlm.nih.gov/pubmed/25532137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3215 |
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