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A Novel Synthesized Sulfonamido-Based Gallate—JEZ-C as Potential Therapeutic Agents for Osteoarthritis

Gallic acid (GA) and its derivatives are anti-inflammatory agents reported to have an effect on osteoarthritis (OA). However, GA has much weaker anti-oxidant effects and inferior bioactivity compared with its derivatives. We modified GA with the introduction of sulfonamide to synthesize a novel comp...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Wei, Shixiu, Lu, Zhenhui, Zou, Yunfeng, Lin, Xiao, Lin, Cuiwu, Liu, Buming, Zheng, Li, Zhao, Jinmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480854/
https://ncbi.nlm.nih.gov/pubmed/26107568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125930
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