Effect of extended-release naltrexone on striatal dopamine transporter availability, depression and anhedonia in heroin-dependent patients

RATIONALE: Extended-release naltrexone (XRNT), an opioid receptor antagonist, is successfully used in the treatment of opioid dependence. However, naltrexone treatment of opioid-dependent patients may reduce striatal dopamine transporter (DAT) availability and cause depression and anhedonia. OBJECTI...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Zaaijer, Eline R., van Dijk, Lonneke, de Bruin, Kora, Goudriaan, Anna E., Lammers, Laureen A., Koeter, Maarten W. J., van den Brink, Wim, Booij, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480848/
https://ncbi.nlm.nih.gov/pubmed/25757673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3891-4
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