Safety, pharmacodynamics, and pharmacokinetics of multiple oral doses of delta-9-tetrahydrocannabinol in older persons with dementia

RATIONALE: Data on safety, pharmacodynamics, and pharmacokinetics of tetrahydrocannabinol (THC) are lacking in dementia patients. METHODS: In this randomized, double-blind, placebo-controlled, crossover trial, we evaluated the safety, pharmacodynamics, and pharmacokinetics of THC in ten patients wit...

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Publicado en:Psychopharmacology (Berl)
Main Authors: Ahmed, Amir I. A., van den Elsen, Geke A. H., Colbers, Angela, Kramers, Cornelis, Burger, David M., van der Marck, Marjolein A., Olde Rikkert, Marcel G. M.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2015
Assuntos:
Original Investigation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480847/
https://ncbi.nlm.nih.gov/pubmed/25752889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3889-y
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