Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas

EGF receptor (EGFR) overexpression is thought to drive head and neck carcinogenesis however clinical responses to EGFR-targeting agents have been modest and alternate targets are actively sought to improve results. Src family kinases (SFKs), reported to act downstream of EGFR are among the alternati...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Veracini, Laurence, Grall, Dominique, Schaub, Sébastien, Divonne, Stéphanie Beghelli-de la Forest, Etienne-Grimaldi, Marie-Christine, Milano, Gérard, Bozec, Alexandre, Babin, Emmanuel, Sudaka, Anne, Thariat, Juliette, Van Obberghen-Schilling, Ellen
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480700/
https://ncbi.nlm.nih.gov/pubmed/25779657
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