TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis

Pancreatic ductal adenocarcinomas (PDACs) overexpress pro-angiogenic factors but are not viewed as vascular. Using data from The Cancer Genome Atlas we demonstrate that a subset of PDACs exhibits a strong pro-angiogenic signature that includes 37 genes, such as HDAC9, that are overexpressed in PDAC...

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Vydáno v:Oncotarget
Hlavní autoři: Gore, Jesse, Craven, Kelly E., Wilson, Julie L., Cote, Gregory A., Cheng, Monica, Nguyen, Hai V., Cramer, Harvey M., Sherman, Stuart, Korc, Murray
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480696/
https://ncbi.nlm.nih.gov/pubmed/25762644
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