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The vls antigenic variation systems of Lyme disease Borrelia: eluding host immunity through both random, segmental gene conversion and framework heterogeneity

Spirochetes that cause Lyme borreliosis (also called Lyme disease) possess the vls locus, encoding an elaborate antigenic variation system. This locus contains the expression site vlsE as well as a contiguous array of vls silent cassettes, which contain variations of the central cassette region of v...

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Detalhes bibliográficos
Publicado no:Microbiol Spectr
Autor principal: Norris, Steven J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480602/
https://ncbi.nlm.nih.gov/pubmed/26104445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/microbiolspec.MDNA3-0038-2014
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