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Ligand-induced formation of nucleic acid triple helices.

We demonstrate that ligand binding can be used to induce the formation of triplex structures that would not otherwise form. Specifically, we show that binding of berenil or 4',6-diamidino-2-phenylindole DAPI) induces formation of the poly(rA).poly(rA).poly(dT) triplex, providing an example of an RNA...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Pilch, D S, Breslauer, K J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1994
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44806/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7524074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.20.9332
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