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Stroke Induces Nuclear Shuttling of Histone Deacetylase 4

BACKGROUND AND PURPOSE: Histone deacetylases (HDACs) 4 and 5 are abundantly expressed in the brain and have been implicated in the regulation of neurodegeneration. Under physiologic conditions, HDACs 4 and 5 are expressed in the cytoplasm of brain cells where they cannot directly access chromatin. I...

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Detalhes bibliográficos
Publicado no:Stroke
Main Authors: Kassis, Haifa, Shehadah, Amjad, Chopp, Michael, Roberts, Cynthia, Zhang, Zheng Gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480163/
https://ncbi.nlm.nih.gov/pubmed/25967576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.009046
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