Ketone Bodies Mediate Anti-Seizure Effects Through Mitochondrial Permeability Transition

OBJECTIVE: Ketone bodies (KB) are products of fatty acid oxidation and serve as essential fuels during fasting or treatment with the high-fat anti-seizure ketogenic diet (KD). Despite growing evidence that KB exert broad neuroprotective effects, their role in seizure control has not been firmly demo...

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Publicat a:Ann Neurol
Autors principals: Kim, Do Young, Simeone, Kristina A., Simeone, Timothy A., Pandya, Jignesh D., Wilke, Julianne C., Ahn, Younghee, Geddes, James W., Sullivan, Patrick G., Rho, Jong M.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480159/
https://ncbi.nlm.nih.gov/pubmed/25899847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24424
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