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Improving efficiency in clinical trials using auxiliary information; Application of a multi-state cure model

In clinical trials, an intermediate marker measured after randomization can often provide early information about the treatment effect on the final outcome of interest. We explore the use of recurrence time as an auxiliary variable for estimating the treatment effect on overall survival in phase thr...

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Detalhes bibliográficos
Publicado no:Biometrics
Main Authors: Conlon, A.S.C., Taylor, J.M.G., Sargent, D.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480062/
https://ncbi.nlm.nih.gov/pubmed/25585942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12281
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