Adenosine accelerates the healing of diabetic ischemic ulcers by improving autophagy of endothelial progenitor cells grown on a biomaterial

Endothelial progenitor cells (EPCs) seeded on biomaterials can effectively promote diabetic ischemic wound healing. However, the function of transplanted EPCs is negatively affected by a high-glucose and ischemic microenvironment. Our experiments showed that EPC autophagy was inhibited and mitochond...

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Publicat a:Sci Rep
Autors principals: Chen, Wen, Wu, Yangxiao, Li, Li, Yang, Mingcan, Shen, Lei, Liu, Ge, Tan, Ju, Zeng, Wen, Zhu, Chuhong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479873/
https://ncbi.nlm.nih.gov/pubmed/26108983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11594
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